PurD RNA motif

purD RNA motif
Predicted secondary structure and sequence conservation of purD
Identifiers
Symbol	purD
Rfam	RF01069
Other data
RNA type	Cis-reg
Domain(s)	Bacteria
SO	0005836

The purD RNA motif is a conserved RNA structure found in epsilonproteobacteria, such as the genera Helicobacter and Campylobacter. The RNA is consistently found in the apparent 5' UTR of purD genes. purD genes encode the enzyme Phosphoribosylamine-glycine ligase, which catalyzes an early step in de novo purine synthesis. Although a possible cis-regulatory role was proposed for this motif, experimental results indicate that it overlaps the 6S RNA of the relevant species, and that the second hairpin of the motif might not be biological.