Pueblo Culhuacán (modern Nahuatl pronunciation ) is an officially designated neighborhood of the Iztapalapa borough of Mexico City, which used to be a major pre Hispanic city. Ancient Culhuacán was founded around 600 CE and the site has been continuously occupied since. The city was conquered by the Aztecs in the 15th century, but the Aztecs considered the city to have status with early rulers marrying into Culhua nobility to legitimize themselves. After the Spanish conquest of the Aztec Empire, the Franciscans and later the Augustinians made Culhuacán a major evangelization center, with the latter building the monastery complex which remains to this day. Today, Culhucan is fully integrated into Mexico City physically and politically. This area was designated as a "Barrio Mágico" by the city in 2011.
Culhuacan is one of the subdivisions of the borough of Iztapalapa, bordering the borough of Coyoacán. Geographically, it is located at the base of the Cerro de la Estrella mountain. Today, the area known as Culhuacan is politically divided into eleven units, called “colonias,” “barrios” or “pueblos” with the historic center designated as Pueblo (village) Culhuacán, due its earlier independent status as an altepetl and then as a recognized pueblo by the Spanish colonial government.
The area was separate and rural as late as early 20th century, made up of chinampas separated by a series of canals. The Culhuacan area is now physically, economically and politically integrated into Mexico City, covered in modern cinderblock and cement structures that continue uninterrupted into neighboring areas.Line 12 of the Mexico City Metro passes through the Pueblo with the elevated station Pueblo Culhuacán only a couple of blocks from the central 16th century monastery complex.