The fiefdom of Guéméné was bought on 26 May 1377, for 3,400 sous d'or by Jean de Rohan, Viscount of Rohan. From his second marriage to Jeanne de Navarre (daughter of Philip III of Navarre) the couple had two children; the eldest Alain became the Viscount of Rohan. That branch became extinct in 1527. The youngest child, Charles, was given the fiefdom of Guéméné.
Charles was the founder of the Guéméné line of the House of Rohan. From this line, stem the Princes of Soubise (founded by François de Rohan) and the Princes of Rochefort (descended from Charles, Prince of Rochefort, son of Charles de Rohan).
The present male line descendants live in Austria, the family having fled France due to the French Revolution.
The present Prince of Guéméné is also a claimant to the Duchy of Bouillon. In 1816, at the Congress of Vienna, it was decided that the family were the rightful heirs to the duchy which had been the property of the House of La Tour d'Auvergne. Through the marriage of Jules and Marie Louise de La Tour d'Auvergne in 1743, the Princes of Guéméné were descendants of the La Tour d'Auvergne family through Marie Louise, whose nephew Jacques de La Tour d'Auvergne (son of her brother the Duke of Bouillon and Mademoiselle de Marsan) was the last Duke of Bouillon.