Frederick Henry Charles of Prussia (Friedrich Heinrich Karl von Preußen; 30 December 1781, Berlin - 12 July 1846, Rome) was a Prussian prince and army officer.
Henry was a son of Frederick William II of Prussia (1744-1797) by his second wife Frederika Louisa (1751-1805), daughter of Louis IX, Landgrave of Hesse-Darmstadt. Henry entered the army on 5 September 1795 as a fähnrich in the Life Company of the 1st Guards Battalion. He also served as an oberst during the 1806-07 campaign against Napoleon - at Auerstadt he was loaned a horse by Gerhard von Scharnhorst after Henry's horse was killed under him. In 1807 he was made commander of the "von Schöning" Infantry Regiment. In the 1813 campaign he was on the headquarters staff of the Russian general Peter Wittgenstein. On 31 Mary 1815 he was promoted to General of Infantry.
From 1800 until the dissolution of the Bailiwick of Brandenburg in 1811, Henry served as co-adjutor of Prince Augustus Ferdinand of Prussia, the Bailiwick's last Lord Master. On its dissolution, Henry's brother Frederick William III of Prussia set up the Royal Prussian Order of Saint John with Augustus as its Grand Master. In 1813 Henry replaced Augustus as Grand Master. Under Henry the new Order set up a hospital in Jüterbog and a 'Deaconess Institute' (Diakonissenanstalt) in Bucharest. He was also a knight of the Order of the Black Eagle, the Iron Cross, the Order of St. Andrew, the Order of St. Alexander Nevsky and the Order of St. George 3rd degree and Knight Grand Cross of the Order of St. Vladimir.