Potassium canrenoate

Potassium canrenoate
Clinical data

AHFS/Drugs.com	International Drug Names
Routes of administration	Intravenous
ATC code	C03DA02 (WHO)
Pharmacokinetic data
Metabolism	Hepatic
Excretion	Renal and fecal
Identifiers
IUPAC name potassium 3-[(8R,9S,10R,13S,14S,17R)- 17-hydroxy-10,13-dimethyl-3-oxo-2,8,9, 11,12,14,15,16-octahydro-1H-cyclopenta[a] phenanthren-17-yl]propanoate
Synonyms	SC-14266
CAS Number	2181-04-6^N
PubChem CID	23671691
DrugBank	DB09015^N
ChemSpider	570975^Y
UNII	M671F9NLEA
ChEMBL	CHEMBL1371200^N
ECHA InfoCard	100.016.868
Chemical and physical data
Formula	C₂₂H₂₉KO₄
Molar mass	396.5616 g/mol
3D model (Jmol)	Interactive image
SMILES [K+].[O-]C(=O)CC[C@]3(O)CC[C@H]2[C@@H]4/C=C\C1=C\C(=O)CC[C@@]1([C@H]4CC[C@@]23C)C
InChI InChI=1S/C22H30O4.K/c1-20-9-5-15(23)13-14(20)3-4-16-17(20)6-10-21(2)18(16)7-11-22(21,26)12-8-19(24)25;/h3-4,13,16-18,26H,5-12H2,1-2H3,(H,24,25);/q;+1/p-1/t16-,17+,18+,20+,21+,22-;/m1./s1^Y Key:JTZQCHFUGHIPDF-RYVBEKKQSA-M^Y
^NY (what is this?)

Potassium canrenoate (INN, JAN) or canrenoate potassium (USAN) (brand names Venactone, Soldactone), also known as aldadiene kalium, the potassium salt of canrenoic acid, is an aldosterone antagonist of the spirolactone group. Like spironolactone, it is a prodrug, and is metabolized to active canrenone in the body.

Potassium canrenoate is notable in that it is the only clinically used antimineralocorticoid which is available for parenteral administration (specifically intravenous) as opposed to oral administration.