Polychlorinated biphenyls
A polychlorinated biphenyl (PCB) is an organic chlorine compound with the formula C12H10−xClx. Polychlorinated biphenyls were once widely deployed as dielectric and coolant fluids in electrical apparatus, carbonless copy paper and in heat transfer fluids. Because of their longevity, PCBs are still widely in use, even though their manufacture has declined drastically since the 1960s, when a host of problems were identified. Because of PCBs' environmental toxicity and classification as a persistent organic pollutant, PCB production was banned by the United States Congress in 1979 and by the in 2001. The International Research Agency on Cancer (IRAC), rendered PCBs as definite carcinogens in humans. According to the U.S. Environmental Protection Agency (EPA), PCBs cause cancer in animals and are probable human carcinogens. Many rivers and buildings including schools, parks, and other sites are contaminated with PCBs, and there have been contaminations of food supplies with the toxins.
Some PCBs share a structural similarity and toxic mode of action with dioxin. Other toxic effects such as endocrine disruption (notably blocking of thyroid system functioning) and neurotoxicity are known. The maximum allowable contaminant level in drinking water in the United States is set at zero, but because of the limitations of water treatment technologies, a level of 0.5 parts per billion is the de facto level.
The bromine analogues of PCBs are polybrominated biphenyls (PBBs), which have analogous applications and environmental concerns.
The compounds are pale-yellow viscous liquids. They are hydrophobic, with low water solubilities — 0.0027-0.42 ng/L for Aroclors, but they have high solubilities in most organic solvents, oils, and fats. They have low vapor pressures at room temperature. They have dielectric constants of 2.5~2.7, very high thermal conductivity, and high flash points (from 170 to 380 °C).
...
Wikipedia