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Pitolisant

Pitolisant
Pitolisant skeletal.svg
Names
IUPAC name
1-{3-[3-(4-Chlorophenyl)propoxy]propyl}piperidine
Other names
BF2.649
Identifiers
3D model (Jmol)
ChemSpider
KEGG
PubChem CID
Properties
C17H26ClNO
Molar mass 295.846 g/mol
Pharmacology
N07XX11 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N  (what is YesYN ?)
Infobox references

Pitolisant (INN) or tiprolisant (USAN) is a histamine receptor inverse agonist/antagonist selective for the H3 subtype. It has stimulant and nootropic effects in animal studies, and may have several medical applications, having been researched for the treatment of narcolepsy, for which it has been granted orphan drug status in the EU and US. It is currently in clinical trials for schizophrenia and Parkinson's disease.

Pitolisant was developed by Jean-Charles Schwartz, Walter Schunack and colleagues after the former discovered H3 receptors. Pitolisant was the first clinically used H3 receptor inverse agonist.



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Wikipedia

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