Piero (or Pietro) Strozzi (c. 1510 – 21 June 1558) was an Italian military leader. He was a member of the rich Florentine family of the Strozzi.
Piero Strozzi was the son of Filippo Strozzi the Younger and Clarice de' Medici.
Although in 1539 he married another Medici, Laudomia di Pierfrancesco, he was a fierce opponent of the main line of that family. He fought in the army led by his father and other Florentine exile from France to oust the Medici from Florence, but, after their defeat at the Battle of Montemurlo, Piero fled to France at the court of Catherine de' Medici.
He was in French service during the Italian War of 1542. Having raised an army of Italian mercenaries, he was confronted by the Imperial-Spanish forces at the Battle of Serravalle, where he was defeated. In 1548 he was in Scotland supporting Mary of Guise of behalf of Henry II of France, during the war of the Rough Wooing. There he designed fortifications against the English at Leith and Haddington. As he was shot in the thigh by an arquebus at Haddington, Strozzi supervised the works at Leith from a chair carried by four workmen. Strozzi also designed works at Dunbar Castle with the assistance of Migiliorino Ubaldini.
In 1551 he successfully defended Mirandola against papal troops during the War of Parma. He was named marshal of France in 1554.