Pierre d'Amboise (1408 – 28 June 1473) was a French nobleman of the House of Amboise. He was a son of Hugh VIII of Amboise, who was killed at the battle of Agincourt, and of Jeanne de Guénand.
On 23 August 1428 he married Anne de Bueil, Dame d'Aubijoux, daughter of Jean IV de Bueil and of Marguerite Dauphine d'Auvergne, countess of Sancerre.
They had 17 children, including:
Pierre d'Amboise died in his castle of Meillant in Berry. On his death he was buried in the nunnery of Order of Poor Ladies he had founded at Bourges.