In Greek mythology, Pholus was a wise centaur and friend of Heracles who lived in a cave on or near Mount Pelion.
The differing accounts vary in details, but each story contains the following elements: Heracles visited his cave sometime before or after the completion of his fourth Labor, the capture of the Erymanthian Boar. When Heracles drank from a jar of wine in the possession of Pholus, the neighboring centaurs smelled its fragrant odor and, driven characteristically mad, charged into the cave. The majority were slain by Heracles, and the rest were chased to another location (according to the mythographer Apollodorus, Cape Maleas) where the peaceful centaur Chiron was accidentally wounded by the arrows of Heracles which were soaked in the venomous blood of the Lernaean Hydra. In most accounts, Chiron surrendered his immortality to be free from the agony of the poison when it came to helping Hercules free Prometheus.
While this pursuit and second combat was occurring, Pholus, back in his cave, accidentally wounded himself with one of the venomous arrows while he was either marveling at how such a small thing could kill a centaur (Apollodorus) or preparing the corpses for burial (Diodoros). He died quickly as a result of the poison's outrageous virulence and was found by Heracles.
Hyginus (in his De Astronomia) reports versions of the story where it is not Pholus's foot on which the poison arrow accidentlly falls, but Chiron's instead.
In the Divine Comedy poem Inferno, Pholus is found with the other centaurs patrolling the banks of the river Phlegethon in the seventh circle of Hell.
It is well known that Chiron, the famously civilized centaur, had origins which differed from those of the other centaurs. Chiron was the son of Cronus and a minor goddess Philyra, which accounted for his exceptional intelligence and honor, whereas the other centaurs were bestial and brutal, being the descendants of the unholy rape of a minor cloud-goddess by the mortal king Ixion. Where Chiron was immortal and could die only voluntarily, the other centaurs were mortal like men and animals.