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Phenyl salicylate

Phenyl salicylate
Skeletal formula
Ball-and-stick model
Names
IUPAC name
Phenyl 2-hydroxybenzoate
Other names
Salol
Identifiers
3D model (Jmol)
ChEBI
ChemSpider
ECHA InfoCard 100.003.873
EC Number 204-259-2
KEGG
MeSH C026041
PubChem CID
Properties
C13H10O3
Molar mass 214.22 g/mol
Appearance White solid
Density 1.25 g/cm3
Melting point 41.5 °C (106.7 °F; 314.6 K)
Boiling point 173 °C (343 °F; 446 K) at 12 mmHg
1 g/6670 mL
-123.2·10−6 cm3/mol
1.615
Pharmacology
G04BX12 (WHO)
Hazards
Flash point 137.3 °C (279.1 °F; 410.4 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N  (what is YesYN ?)
Infobox references

Phenyl salicylate, or salol, is a chemical substance, introduced in 1886 by Marceli Nencki of Basel. It can be created by heating salicylic acid with phenol. Once used in sunscreens, phenyl salicylate is now used in the manufacture of some polymers, lacquers, adhesives, waxes and polishes. It is also used frequently in school laboratory demonstrations on how cooling rates affect crystal size in igneous rocks.

In the salol reaction, phenyl salicylate reacts with o-toluidine in 1,2,4-trichlorobenzene at elevated temperatures to the corresponding amide o-Salicylotoluide.Salicylamides are one type of drug.

It has been used as an antiseptic based on the antibacterial activity upon hydrolysis in the small intestine.

It acts as a mild analgesic.


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Wikipedia

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