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Perilla alcohol

Perillyl alcohol
(+)-Perillyl alcohol.svg
(R)-(+)-Perillyl alcohol
(-)-Perillyl alcohol.svg
(S)-(-)-Perillyl alcohol
Names
IUPAC name
(4-Isopropenyl-1-cyclohexen-1-yl)methanol
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.007.856
PubChem CID
Properties
C10H16O
Molar mass 152.24 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Perillyl alcohol (IUPAC name: [4-(prop-1-en-2-yl)cyclohex-1-en-1-yl]methanol) and its precursor limonene are naturally occurring monocyclic terpenes derived from the mevalonate pathway in plants. Perillyl alcohol can be found in the essential oils of various plants, such as lavender, lemongrass, sage, and peppermint. It has a number of manufacturing, household, and medical applications. For example, perillyl alcohol may be used as an ingredient in cleaning products and cosmetics, and as of 2015 it was in development as a potential treatment for people with brain cancer.

Perillyl alcohol is a metabolite of limonene, which itself is formed from geranyl pyrophosphate in the mevalonate pathway. Conversion of limonene to perillyl alcohol is accomplished via hydroxylation by enzymes that belong to the superfamily of proteins. Perillyl alcohol can be metabolized further to perillaldehyde (perillyl aldehyde) and perillic acid.


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Wikipedia

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