The Patternist series (also known as the Patternmaster series or Seed to Harvest) is a group of science fiction novels by Octavia E. Butler that detail a secret history continuing from the Ancient Egyptian period to the far future that involves telepathic mind control and an extraterrestrial plague. A profile of Butler in Black Women in America notes that the themes of the series include "racial and gender-based animosity, the ethical implications of biological engineering, the question of what it means to be human, ethical and unethical uses of power, and how the assumption of power changes people."
Butler's first published novel, 1976's Patternmaster, was the first book in this series to appear. From 1977 until 1984, she published four more Patternist novels: Mind of My Mind (1977), Survivor (1978), Wild Seed (1980) and Clay's Ark (1984). Until Butler began publishing the Xenogenesis trilogy in 1987, all but one of her published books were Patternist novels (1979's Kindred was the exception).
Butler later expressed a dislike for the novel Survivor, and declined to bring it back into print.
Chronologically, the series starts with the fourth novel published, Wild Seed. Set in the 17th and 18th centuries, the story involves the relationship between two immortals - Doro, a man born in Africa thousands of years ago, who survives by transferring his consciousness from one body to another (feeding on each new victim's mental energy in the process), and Anyanwu, a shape-shifter with perfect control over her body. They struggle to live together over generations as Doro attempts to create a new race through a selective breeding program.