Sir Patrick Hepburn of Waughton and Luffness, Knt., (d. Bef. November 1649) was a Scottish laird and notable Covenanter from East Lothian. In 1639-1641 Sir Patrick was a member for Haddingtonshire in the Scottish Parliament.
Sir Patrick Hepburn of Waughton and Lufness, knight, was Retoured heir to his father, Patrick Hepburn of Wauchtoun, on 3 April 1605.
In the National Archives is an extract of a Discharge by Sir Patrick Hepburne of Wauchtoun, Knt., in favour of George Keith, 5th Earl Marischal, and Dame Margaret Ogilvie, his spouse, for £20,500 Scots for the lands of Brethertoun [Brotherton] dated 8 December 1613.
On 10 January 1639, George Lauder of The Bass, and his mother (Sir Patrick's sister) Isobel Hepburne, Lady Bass, being both Royalists and having spent much time at Court with Charles I and fearing forfeiture, assigned the barony of The Bass and a string of other properties to Sir Patrick Hepburn of Waughton. In a Supplication dated 15 September 1641, by Sir Patrick Hepburn of Wauchtoun, knight, addressed to the King and the Estates of Parliament, he mentions that "he has lately acquired the right of the lands of Popill and Auld Haddington from the Laird of The Bass." In another charter, confirmed at Edinburgh 15 November 1641, Sir Patrick Hepburn of Waughton is confirmed in many properties including lands and 'acres' in Morham and 14 husbandlands (364 acres) in Garvald, East Lothian also previously owned George Lauder of Bass.
Between 1644 until his death, Sir Patrick was engaged in a dispute with the Earl of Home over possession of Fast Castle, and the rents of Auldcambus.
Sir Patrick was a Lieutenant-Colonel who raised a 400 strong infantry regiment in East Lothian, which served in General Leslie's army of the Covenant, entering England on 20 August 1640. Sir Patrick was one of the commissioners to the negotiations at Ripon in Yorkshire. The regiment served at the sieges of York and Newcastle-upon-Tyne and at the battle of Marston Moor. "Wauchtoun's regiment" with Sir Patrick Hepburn as commander is recorded as being quartered and then in skirmishes with the Royalists at Todcaster and York in April 1644.