The path integral formulation of quantum mechanics is a description of quantum theory that generalizes the action principle of classical mechanics. It replaces the classical notion of a single, unique classical trajectory for a system with a sum, or functional integral, over an infinity of quantum-mechanically possible trajectories to compute a quantum amplitude.
This formulation has proven crucial to the subsequent development of theoretical physics, because manifest Lorentz covariance (time and space components of quantities enters equations in the same way) is easier to achieve than in the operator formalism of canonical quantization. Unlike previous methods, the path integral allows a physicist to easily change coordinates between very different canonical descriptions of the same quantum system. Another advantage is that it is in practice easier to guess the correct form of the Lagrangian of a theory, which naturally enters the path integrals, than the Hamiltonian. Possible downsides of the approach include that unitarity (this is related to conservation of probability; the probabilities of all physically possible outcomes must add up to one) of the S-matrix is obscure in the formulation. The path-integral approach has been proved to be equivalent to the other formalisms of quantum mechanics and quantum field theory. Thus, by deriving either approach from the other, problems associated with one or the other approach (as exemplified by Lorentz covariance or unitarity) go away.
The path integral also relates quantum and processes, and this provided the basis for the grand synthesis of the 1970s, which unified quantum field theory with the statistical field theory of a fluctuating field near a second-order phase transition. The Schrödinger equation is a diffusion equation with an imaginary diffusion constant, and the path integral is an analytic continuation of a method for summing up all possible random walks.