The Palouse (/pəˈluːs/ pə-LOOSS) is a region of the northwestern United States, encompassing parts of southeastern Washington, north central Idaho and, by some definitions, parts of northeast Oregon. It is a major agricultural area, primarily producing wheat and legumes. Situated about 160 miles (260 km) north of the Oregon Trail, the region experienced rapid growth in the late 19th century and was once Washington's most populous region, surpassing even the Puget Sound area.
The Palouse is home to two land grant universities, the University of Idaho in Moscow and Washington State University in Pullman. Just eight miles (13 km) apart, both schools opened in the early 1890s.
The origin of the name "Palouse" is unclear. One theory is that the name of the Palus tribe (spelled in early accounts variously as Palus, Palloatpallah, Pelusha, etc.) was converted by French-Canadian fur traders to the more familiar French word pelouse, meaning "land with short and thick grass" or "lawn." Over time, the spelling changed to Palouse. Another theory is that the region's name came from the French word and was later applied to its indigenous inhabitants.