The Palazzo Fantuzzi is a monumental Renaissance style palace located on Via San Vitale number 23 in central Bologna. It rises near the church of Santi Vitale e Agricola.
While attributed by some to Sebastiano Serlio or Baldassare Peruzzi, the palace was designed in 1517 by Andrea da Formigine. The facade with the ashlar columns was commissioned in 1521 by Francesco Fantuzzi; the carved elephants with towers above the corner niches refer to the senatorial family coat of arms. The coat of arms was a pun on the ele-fantuzzi family.
The interior courtyard has a monumental Baroque staircase designed in 1680 by Paolo Canali. The statuary at the top of the stairs is by Gabriele Bunelli. The piano nobile has a room painted with quadratura (1684) by Francesco Galli Bibiena and other rooms were frescoed by Angelo Michele Colonna. Part of the palace is now used for exhibitions.