"Karmacoma" is a single by British trip hop collective Massive Attack, released as a third and final single from their second album Protection on 20 March 1995. It is a rap featuring vocals from band members 3D and Tricky. Tricky also recorded his own version of "Karmacoma", renamed "Overcome" for his debut studio album, Maxinquaye.

Massive Attack themselves recorded a second version of the song (without Tricky) renamed "Fake The Aroma" on "The Help Album", a compilation album for the charity War Child.

The melodic refrain (e.g. 0:54) is taken from the opera Prince Igor by Russian composer Alexander Borodin, and also includes a sample of Tuvan throat singing used by The KLF in "Dream Time in Lake Jackson". The bass line sample featured is the same bass line used by Serge Gainsbourg in the song "Melody" from his 1971 album Histoire de Melody Nelson. The "Napoli Trip Mix", by Italian band Almamegretta, of the song contains samples from Roberto Paci Dalò's record "Napoli", released in 1993. The Startled Insects wrote the music for this track (Tim Norfolk and Bob Locke)

Tricky remade "Karmacoma" for his 1995 debut album Maxinquaye under the title "Overcome", enlisting Martina Topley-Bird to sing his lyrics and incorporating a sample of Shakespears Sister's 1992 song "Moonchild". David Bennun from The Quietus later called his version "a thick, unquiet fever dream - and an almost cubist vision of a moment in time that encompasses within the same frame a couple walking through quiet suburbs as the Gulf War rages three thousand miles away". In an interview for Melody Maker, Tricky was asked about the sexual nature of the song and other material on Maxinquaye, to which he responded:

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