Otto Henry of Sulzbach (22 July 1556 – 29 August 1604) was the Count Palatine of Sulzbach from 1569 until 1604.
Otto Henry was born in Amberg in 1556 as one of five sons of Wolfgang, Count Palatine of Zweibrücken. After his father's death in 1569, his lands were partitioned between Otto Henry and his four brothers — Otto Henry received the territory around Sulzbach-Rosenberg. Otto Henry died in Sulzbach in 1604 and was buried in Lauingen. Without any surviving sons, Sulzbach was inherited by his brother Philip Louis of Palatinate-Neuburg.
Otto Henry married Dorothea Maria of Württemberg (3 September 1559 – 23 March 1639), daughter of Duke Christopher, on 25 November 1582 and had the following children: