Osteosclerotic
| Osteosclerosis | |
|---|---|
 |
|
| Sclerosis of the bones of the pelvis due to prostate cancer metastases | |
| Classification and external resources | |
| Specialty | medical genetics |
| ICD-10 | M85.8, Q77.4 |
| ICD-9-CM | 756.52 |
| DiseasesDB | 15823 |
| MeSH | D010026 |
Osteosclerosis is a disorder that is characterized by abnormal hardening of bone and an elevation in bone density. It may predominantly affect the medullary portion and/or cortex of bone. Plain radiographs are a valuable tool for detecting and classifying osteosclerotic disorders. It can manifest in localized or generalized osteosclerosis. Localized osteosclerosis can be caused by Legg–Calvé–Perthes disease, sickle-cell disease and osteoarthritis among others. Osteosclerosis can be classified in accordance with the causative factor into acquired and hereditary.
In the animal kingdom there also exists a non-pathological form of osteosclerosis, resulting in unusually solid bone structure with little to no marrow. It is often seen in aquatic vertebrates, especially those living in shallow waters, providing ballast as an adaptation for an aquatic lifestyle. It makes bones heavier, but also more fragile. In those animal groups osteosclerosis often occurs together with bone thickening (pachyostosis). This joint occurrence is called pachyosteosclerosis.
Sclerosis of the bones of the thoracic spine due to prostate cancer metastases (CT image)
Sclerosis of the bones of the thoracic spine due to prostate cancer metastases (CT image)
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Wikipedia