Osmosis Jones
| Osmosis Jones | |
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Theatrical release poster
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| Directed by |
Animation: Tom Sito Piet Kroon Live-action: Robert Farrelly Peter Farrelly |
| Produced by | Dennis Edwards Robert Farrelly Peter Farrelly Zak Penn Bradley Thomas |
| Written by | Marc Hyman |
| Starring |
Chris Rock Laurence Fishburne David Hyde Pierce Brandy Norwood William Shatner Molly Shannon Chris Elliott Bill Murray |
| Music by | Randy Edelman |
| Cinematography | Mark Irwin |
| Edited by | Lois Freeman-Fox Stephen Schaffer Sam Seig |
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Production
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| Distributed by | Warner Bros. Pictures |
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Release date
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Running time
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95 minutes |
| Country | United States |
| Language | English |
| Budget | $70 million |
| Box office | $14 million |
Osmosis Jones is a 2001 American live-action/animated buddy cop comedy film with animated scenes directed by Tom Sito and Piet Kroon and live-action scenes directed by the Farrelly brothers. The film centers on Frank Detorre, a slovenly zookeeper; the live-action scenes are set outside Frank's body, while the animated scenes are set inside his body, which is portrayed as a city inhabited by anthropomorphic microorganisms. White blood cell cop Osmosis "Ozzy" Jones and cold pill Drix must prevent deadly virus Thrax from killing Frank within forty-eight hours.
The film was met with mixed reviews, with critics praising the animated portions but criticizing the live-action portions and their use of gross-out humor. The film was a box office bomb, earning $14 million against a budget of $70 million, though it later sold well in home media. It also served as the pilot to the Kids' WB television series Ozzy & Drix (2002–04), where Ozzy and Drix get transferred by a mosquito to the body of a teenage boy named Hector and continue their battle against germs and viruses from there.
Frank Detorre (Bill Murray) is an unkempt, slovenly zookeeper at the Sucat Memorial Zoo in Rhode Island. Depressed by the loss of his wife years earlier, he copes by unhealthy eating and ignoring basic hygiene, to the annoyance of his young daughter Shane (Elena Franklin).
Inside the body, Osmosis "Ozzy" Jones (Chris Rock) is a rebellious white blood cell officer of the Frank PD, who was fired from his job working in the kidneys and was demoted to patrol duty in the mouth after an incident at the science fair where he caused Frank to accidentally vomit on Shane's science and P.E. teacher, Mrs. Boyd (Molly Shannon). Facing a challenge to his re-election prospects, Mayor Phlegmming (William Shatner) doubles down on his junk-food policies, ignoring their effect on Frank's health. This causes Frank to eat a boiled egg covered in filth, allowing Thrax (Laurence Fishburne), a deadly virus, to enter the throat. Unwilling to admit responsibility, Phlegmming instructs Frank to take a cold pill through brain signals. The suppressant, Drixenol "Drix" Koldreliff (David Hyde Pierce), proceeds to disinfect the throat, covering up any evidence of Thrax's arrival. To his displeasure, Ozzy is subsequently assigned to assist Drix in his investigation.
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