"On My Own" was a Billboard #1 hit duet by singers Patti LaBelle and Michael McDonald when it was released as a single in 1986. It was released from LaBelle's first platinum album, Winner in You and was written and produced by Burt Bacharach and his former wife Carole Bayer Sager. The song was originally recorded by singer Dionne Warwick for inclusion on her album Friends. It is unclear why the song was not included on the final track list. The song was based on a relationship that had reached its end with both parties going their separate ways in a melancholy state with the occasional option of coming back together again one day.

It was often stated the two performers were in separate cities when they recorded their individual parts which were then "married" during mixing. This was reflected in the music video produced to promote the song, which depicted LaBelle and McDonald performing the song simultaneously on different coasts. The singers were shown on separate sides of a split screen, each singing the song while walking through apartments which had identical layouts but different decor and furniture. The views from their respective porches, where they finished the song, made clear their separation by the continent.

The song became the biggest hit single ever for both singers as it reached number one on the Billboard chart for 3 weeks, as well as charting highly on the R&B and Adult Contemporary charts. In the UK, the song peaked at number two on the UK Singles Chart, going gold (it was the 22nd best-selling single of 1986 in the UK). The song was initially not intended to be a duet at all, but LaBelle decided to invite McDonald to help her turn the song into a duet, as she stated: "The song was sent to me and I did a version of it but somehow it just didn't quite work. We were going over things I'd done and we talked about turning it into a duet. Someone asked, 'If you could do it with anyone, who would you sing it with?', and Michael was my first choice."

In September 1995, country entertainer Reba McEntire released the song as the first single from her album Starting Over. Her version, featuring guest vocals from Martina McBride, Linda Davis, and Trisha Yearwood peaked at #20 on Hot Country Singles & Tracks chart, although only McEntire received chart credit for it. Its music video was directed by Dominic Orlando and was filmed on the Chaplin Stage.

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