Ohio Second Congressional District Election, 2005

Elections were held in Ohio's 2nd congressional district on August 2, 2005, to choose a United States Representative to replace Rob Portman, who resigned his seat on April 29, 2005, to become United States Trade Representative. Jean Schmidt, the Republican Party candidate, defeated Democrat Paul Hackett, in a surprisingly close election as the district has not elected a Democrat since Tom Luken won a 1974 special election.

The district is the 57th most Republican congressional district in the nation by the reckoning of the Cook Political Report. It stretches along the Ohio River from the Hamilton County suburbs of Cincinnati east to Scioto County, and includes all of Adams, Brown Pike, and Clermont counties and parts of Hamilton, Scioto and Warren counties.