The O'Byrne family (Irish: Ó Broin) is an Irish clann that descend from Bran mac Máelmórda, King of Leinster, of the Uí Faelain of the Uí Dúnlainge. Before the Norman invasion of Ireland they began to colonise south Wicklow.
The seat of the most famous branch of the Ó Broin (Uí Broin or Branaigh) was at Ballinacor and controlled the surrounding lands, part of Crioch Branach.
During the Desmond Rebellions, the warlord Hugh O'Byrne gave support to the Earl of Desmond, and died during the second rebellion. His son Fiach McHugh O'Byrne took over the chieftainship and together with the Pale lord James Eustace, 3rd Viscount Baltinglass, continued hostilities to the English administration. A large English force under the Lord Deputy of Ireland Earl Grey de Wilton was sent to subdue them, only to be ambushed and defeated at the battle of Glenmalure on 25 August 1580, losing over 800 dead. Feagh also helped in the escape of Hugh Roe O'Donnell from Dublin Castle in 1591 and Hugh Roe stayed with O'Byrne at Ballinacor, Glenmalure.
In 1595, Ballinacor was occupied by an Tudor garrison, with Feagh later expelling the garrison, and destroying the fort. Feagh was betrayed and killed by the forces of the Lord Deputy of Ireland at Fananerin on 8 May 1597. He was drawn and quartered and his head was sent to Dublin Castle and placed on a spike. The head was later pickled and sent to England.