"Nothing's Gonna Stop Us Now" is a song co-written by Albert Hammond and Diane Warren, recorded by the American rock band Starship in 1986. It is a duet featuring Starship vocalists Grace Slick and Mickey Thomas. Featured as the theme to the romantic comedy film Mannequin, it hit No. 1 in the Billboard Hot 100 on April 4, 1987 and reached No. 1 on the UK Singles Chart for four weeks the following month and became the UK's 2nd biggest selling single of 1987. The song also reached the top 10 in six European countries. The single became the first number one single by songwriter Diane Warren. At the time, it made Grace Slick (aged 47) the oldest woman to have a number one single in the United States though the record was later broken by Cher's "Believe" in 1999 (aged 52).

The song also received an Academy Award nomination for "Best Original Song" at the 60th Academy Awards. In addition to appearing on the Mannequin soundtrack, the song was also released on Starship's album No Protection in July 1987. The music video was released in late 1986 to promote Mannequin.

In a radio interview, Albert Hammond said that the idea for the song came from his impending marriage to his live-in girlfriend of seven years, after his divorce from his previous wife was finalized. He had said to Diane Warren, "It's almost like they've stopped me from marrying this woman for seven years, and they haven't succeeded. They're not gonna stop me doing it." The song has been considered "feel good" propelled by a strong synthesizer beat.

A music video (released in 1986) was produced for the song. It shows Mickey Thomas pursuing a mannequin come to life, played by Grace Slick, wrapped around footage from the film. Meshach Taylor, who plays window dresser Hollywood Montrose in the film, makes a cameo. It has more than 15 million views on YouTube as of March 11, 2017.

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