North Quay is a location in the Brisbane central business district and the name of street in the same area, running along the Brisbane River from an intersection near Makerston Street to the top of the Queen Street.
The small locality is roughly the area of four city blocks in length, from the Ann Street north of Brisbane Square to Queens Gardens and includes the Conrad Treasury Casino.
A riverside bikeway leading to the University of Queensland and the western suburbs from the Victoria Bridge has been built on the river at North Quay.
The location has a historical record in Queensland because it was a landing point during the first European exploration of the river in 1823 and later in 1825, the Moreton Bay penal colony at Redcliffe relocated here, establishing the first permanent European settlement in what was to become the state of Queensland. Captain Henry Miller was responsible for the settlement transfer, which was due to unfriendly aborigines, biting insects and a lack of reliable fresh water at Redcliffe. Although North Quay is most likely not the exact location selected by John Oxley and Sir Thomas Brisbane during scouting expeditions in November 1824, the high banks at North Quay proved to be highly suitable, well above the flood levels that plagued Brisbane in subsequent years.
The road can be congested on week days with traffic from Coronation Drive using part of the street to enter the city. The road also feeds traffic onto the Riverside Expressway, one end of the Pacific Motorway.