No More Mr. Nice Guy (House)

"No More Mr. Nice Guy" is the 13th episode of the fourth season of House, and the 83rd episode overall. It was the first House episode filmed after the resolution of the 2007–2008 Writers Guild of America strike. It aired in the United States on April 28, 2008.

The episode revolves around Dr. Gregory House (Hugh Laurie) noticing a man named Jeff (Paul Rae) in the emergency room, whom he thinks is "too nice". House thinks that Jeff's inability to get mad is a symptom of an underlying condition and decides to find out what is wrong with him. Meanwhile, Dr. Eric Foreman (Omar Epps), thinks the other diagnostic team members don't respect him, while Amber Volakis (Anne Dudek) and House try to create a deal in which they can both spend time with Dr. James Wilson (Robert Sean Leonard).

"No More Mr. Nice Guy" was watched by approximately 14 million viewers, making it the night's second most watched program, behind Dancing with the Stars. The episode gained mixed reviews from critics. Mary McNamara of the Los Angeles Times stated that the episode was "the worst House episode ever", while Gina Dinunno of TV Guide commented that she thought the episode was "pretty good".

The local nurses' union for the Princeton-Plainsboro Teaching Hospital is on strike. Jeff, the husband of Deb (Chad Morgan), one of the nurses, collapses while walking the picket line. At the emergency room, House suspects Jeff's extreme niceness and inability to get angry is a major symptom of an underlying condition. After various tests, the team suspects his niceness is a personality change resulting from syphilis. Kutner (Kal Penn) asks the couple if either of them had an affair, which could lead to syphilis. Deb denies it, stating that it is just the way her husband behaves and that it is impossible for her to not love him.