Nicole Byer is a comedian and actress who starred in the scripted comedy based on her life, Loosely Exactly Nicole, as well as prank show Ladylike. Byer has also appeared in the sketch-comedy series Party Over Here, reality show Girl Code, and the Upright Citizens Brigade.
Byer has described Whoopi Goldberg, Tina Turner and Mo'Nique as early inspirations for her career in the entertainment industry. Byer moved to New York City after high school, waitressing and taking classes at the Upright Citizens Brigade before moving to Los Angeles in 2012.
At The Ringer, Allison P. Davis described Byer's comedy as "most easily compared to a raunchier Retta with a hint of Ilana Glazer’s madcap energy. She’s mouthy, vulgar, a little bit goofy, relatable but ridiculously charming, and not afraid to infuse her broad comedy with a confident sexuality." Writing for USA Today, Jaleesa M. Jones said "it's precisely [Byer's] brazen, ribald brand of comedy that landed her in the creative incubator that is MTV, where she toplines two new comedy shows" in 2016, Ladylike and Loosely Exactly Nicole."
Byer and Sasheer Zamata created a web series called Pursuit of Sexiness. Nayomi Reghay at The Daily Dot called it a "must-see".
Byer appears on the MTV reality show Girl Code, where Maitri Mehta said at Bustle Byers is a "beloved talking head"; Stephanie Merry at The Washington Post called Byer "one of the most dependably funny commentators" on the show. She also hosted MTV's Are You the One? The Aftermatch Live, an after-show for the second season of Are You the One?.