Nicolò Albertini, O.P. (c. 1250 – 27 April 1321), was an Italian Dominican friar, statesman, and cardinal.
Albertini was born about 1250 in the city of Prato, then in the County of Prato, part of the Holy Roman Empire, to parents who both belonged to illustrious families of Tuscany.
Albertini's early education was directed by his parents. At the age of sixteen (1266) he entered the novitiate of the Dominican Order at the Priory of Santa Maria Novella in Florence, and, upon his profession of religious vows the following year, was sent to the University of Paris to complete his studies.
Albertini preached throughout Italy with success, and his theological lectures were especially well attended at Florence and at Rome. He served as lector at the studium at Santa Maria sopra Minerva which had developed from the studium at the first Dominican Roman studium at the Convent of Santa Sabina. He was entrusted by his superiors with various important duties and governed several houses. He was made Procurator General of the whole Order of St. Dominic by Blessed Nicolo Bocassini, then Master General, and was afterwards elected Prior Provincial of the Roman Province. In 1299 Pope Boniface VIII appointed him Bishop of Spoleto and soon afterwards sent him as Papal Legate to the Kings of France and England, Philip IV and Edward I, with a view to reconciling them, a seemingly hopeless task.