ncRNA Repressor of NFAT (nuclear factor of activated T cells) | |
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Predicted secondary structure and sequence conservation of NRON
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Identifiers | |
Symbol | NRON |
Rfam | RF00636 |
Other data | |
RNA type | Gene |
Domain(s) | Eukaryota |
SO | 0001263 |
NRON also known as ncRNA repressor of the nuclear factor of activated T cells is a non-coding RNA involved in repressing NFAT. The function of this ncRNA was identified by a large-scale screen of 512 non-coding RNAs discovered in earlier EST sequencing projects.
Each of the RNAs that were conserved between human and mouse were knocked down using shRNAs. The resulting cell-lines were screened for changes in activity of NFAT.