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NRON

ncRNA Repressor of NFAT (nuclear factor of activated T cells)
NRON secondary structure.jpg
Identifiers
Symbol NRON
Rfam RF00636
Other data
RNA type Gene
Domain(s) Eukaryota
SO 0001263

NRON also known as ncRNA repressor of the nuclear factor of activated T cells is a non-coding RNA involved in repressing NFAT. The function of this ncRNA was identified by a large-scale screen of 512 non-coding RNAs discovered in earlier EST sequencing projects.

Each of the RNAs that were conserved between human and mouse were knocked down using shRNAs. The resulting cell-lines were screened for changes in activity of NFAT.



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Wikipedia

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