My Sister Eileen is a series of autobiographical short stories by Ruth McKenney, originally published in The New Yorker, which eventually inspired many other works: My Sister Eileen (a 1938 book), a play, a musical, a radio play (and an unproduced radio series), two motion pictures, and a CBS television series in the 1960–1961 season.
The stories center on two sisters from Ohio who are out to make successful careers while living in a basement apartment in the Greenwich Village section of New York City. Older, sensible Ruth aspires to be a writer, while Eileen dreams of success on the stage. A variety of oddball characters bring color and humor to their lives.
The stories were adapted for the stage by Joseph Fields and Jerome Chodorov. The Broadway production, directed by George S. Kaufman, opened on December 26, 1940 at the Biltmore Theatre and moved three times before finally completing its run of 864 performances on January 16, 1943. The opening night cast included Shirley Booth as Ruth and Jo Ann Sayers as Eileen, with Richard Quine and Morris Carnovsky in supporting roles.
Eileen McKenney, the inspiration for the title character, and her husband, novelist and screenwriter Nathanael West, were killed in a Southern California car accident four days before the Broadway opening.
Fields and Chodorov adapted their play for a 1942 film released by Columbia Pictures (their biggest hit of 1942/3). Alexander Hall directed a cast that includes Rosalind Russell as Ruth and Janet Blair as Eileen, with Brian Aherne, George Tobias, Allyn Joslyn, Elizabeth Patterson, Grant Mitchell, Jeff Donnell, and Richard Quine in supporting roles.