Muhammadan Anglo-Oriental College was founded in 1875. The college started as a primary school on Queen Victoria's birthday, 24 May 1875 known as Muhammedan Anglo Oriental Collegiate School. It was established as Madrasatul Uloom Musalmanan-e-Hind in 1875 and after two years it became Muhammadan Anglo-Oriental College. The Anglo–Indian statesman Sir Syed Ahmad Khan founded the predecessor of AMU, the Muhammadan Anglo Oriental College, in 1875 having already established two schools. The movement of Muslim awakening associated with Syed Ahmad Khan and M.A.O. College came to be known as Aligarh Movement. He considered competence in English and "Western sciences" necessary skills for maintaining Muslims' political influence, especially in Northern India. Khan's image for the college was based on his visit to Oxford and Cambridge and he wanted to establish an education system similar to the British model.
Sir Syed nursed the institution at a time when English education was a tabo o.In 1878 intermediate and in 1881 B.A classes were started. In 1881, a civil service preparatory class was started for aspiring students. In 1887 it began to prepare students to enter the Engineering college at Roorkee.
In the beginning the college was affiliated with the University of Calcutta for the matriculation examination but became an affiliate of Allahabad University in 1885. In 1877 the school was raised to college level and Lord Lytton laid the foundation stone of the college building.
The college also published a magazine by its name.
Sir Syed said that their intention was to establish a university. It was the predecessor of Aligarh Muslim University.