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Monica Riley

Monica Riley
Born 1926
Died (2013-10-11)October 11, 2013
Richmond, California

Monica Riley (1926 - October 11, 2013) was an American scientist who contributed to the discovery of messenger RNA in her Ph.D work with Arthur Pardee, and was later a pioneer in the exploration and computer representation of the Escherichia coli genome.

After graduating Smith College with a chemistry degree in 1947, she studied Biochemistry at University of California Berkeley with Pardee. Her Ph.D. work, together with the PaJaMo experiment, ruled out ribosomes as carriers of information to synthesize protein, leading the discovery of messenger RNA. After holding faculty positions at University of California Davis and SUNY Stony Brook, she moved to the Marine Biological Laboratory in Woods Hole, staying there until age 80. During this time, she helped launch the EcoCyc database of Escherichia coli metabolism and developed classification systems for genes and proteins which were forerunners of gene ontology.



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