Miles Laurence is a fictional character from ABC's daytime drama One Life to Live. He was portrayed by David Chisum from February 12, 2007, to April 22, 2008.

The deceased Dr. Spencer Truman leaves his estate to the mysterious Miles Laurence in 2007. Miles is a former patient of Spencer's whose face had been horribly disfigured. As an infant, Miles had been given up to a local hospital by his "fire and brimstone" preacher father upon seeing the extent of his deformities. Years later, Spencer restored Miles' face and gained Miles' friendship and loyalty. The soft-spoken Miles defends Spencer, the only friend he has ever had, to the many residents of Llanview who rightfully hate the villainous doctor. Miles' loyalty to Spencer makes him an enemy of Spencer's nemesis Todd Manning.

Miles soon reveals to Jessica Buchanan that he is the brother of deceased Llanview villain Mitch Laurence — Jessica's biological father — and Walker Laurence. To help integrate himself into society, Miles sees psychiatrist Marty Saybrooke; he soon falls for her. Marty relinquishes him as a patient so that they can be friends, but makes it clear to Miles that she has no romantic interest in him.

Intensely sheltered with a skewed view of the world and morality, Miles is determined to "make" Marty love him. Miles has three men attack Marty so that he can come to her rescue, and he later blackmails her into marrying him with her taped "confession" to Spencer's murder. After Todd is stabbed and kidnapped, it is revealed that Miles had paid a young man named Hunter Atwood to do the deed, both to protect his benefactor Spencer's secret (that Todd's son with Margaret Cochran was adopted by Michael and Marcie McBain) and to make Todd pay for his vicious rape of Marty years before. When Hunter leaves an unconscious Todd on his doorstep, Miles hides Todd in a storage room and then dumps him outside, but not before Marty's son Cole Thornhart discovers him. Miles compels Cole to keep his secret to protect Marty from arrest for Spencer's murder. But Cole and Marty soon admit all they know to the police; Miles is arrested, and Todd is found alive.

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