The side-to-side isoperistaltic strictureplasty (SSIS), also now known as the Michelassi Stricureplasty, was designed to avoid sacrificing large amounts of small bowel in case of long segments of stricturing Crohn’s disease.
In this strictureplasty the long loop of the bowel affected by Crohn’s disease is first divided at its midpoint. The two halves are then moved side to side. A very long opening is created between two loops, which are then sutured together.
The recent extension of this technique to Crohn’s disease of the last portion of the small bowel going into the right colon (terminal ileum) is poised to change the paradigm of surgical treatment of terminal ileitis from a conventional resection (ilecolectomy) to a bowel sparing procedure (SSIS).