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Michaelis-Menten kinetics


In biochemistry, 'Michaelis–Menten' kinetics is one of the best-known models of enzyme kinetics. It is named after German biochemist Leonor Michaelis and Canadian physician Maud Menten. The model takes the form of an equation describing the rate of enzymatic reactions, by relating reaction rate to , the concentration of a substrate S. Its formula is given by

This equation is called the Michaelis–Menten equation. Here, represents the maximum rate achieved by the system, at saturating substrate concentration. The Michaelis constant is the substrate concentration at which the reaction rate is half of . Biochemical reactions involving a single substrate are often assumed to follow Michaelis–Menten kinetics, without regard to the model's underlying assumptions.


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