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This list of Resident Evil characters includes major characters that were introduced in the Resident Evil series of live-action horror films. The characters are described, below, using in-universe tone.

Alice (portrayed by Milla Jovovich) is the protagonist of the Resident Evil film series. The plot of each film generally revolves around her struggle with the Umbrella Corporation. Alice also appears in the film's novelizations which go into greater detail of her backstory

In the first film, Resident Evil, Alice is depicted as suffering from amnesia, gradually realizing her abilities as a highly trained private security operative. In Resident Evil: Apocalypse and Resident Evil: Extinction, her character is represented as "a supremely efficient killing machine" and bio-weapon. Alice is an "iconic figure and is closely associated with the series," becoming more skilled and rugged throughout the series. Alice's superhuman abilities, as well as the use of various styles of martial arts and gunplay make her something of a superhero character. For example, in Resident Evil: Apocalypse, after her exposure to the T-virus, she displays psychic powers akin to those of Alexia Ashford. In Extinction, her powers are even more developed - she displays even greater control over her telekinesis (although she experiences blackouts and massive headaches if she pushes her powers too far). In Resident Evil: Afterlife, Alice's superhuman abilities have been taken away by Albert Wesker, who injected her with a serum that disabled her T-virus cells; however, at the end of Resident Evil: Retribution, Wesker injects her with the T-Virus and restores her powers, saying that Alice and her powers are the last, best hope for humanity. In Resident Evil: The Final Chapter, after being betrayed by Wesker, Alice undertakes a final mission into the Hive with the help of Claire Redfield and the Red Queen to save what is left of humanity. In this movie, she displays none of her powers despite Wesker restoring them at the end of Retribution though the Red Queen makes a comment about Wesker pretending to restore her powers permanently.


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