The Mayfair Inn Open was a PGA Tour event that was played for four years in the 1950s. The Mayfair Inn was a 155-room resort hotel on the shores of Lake Monroe in Sanford, Florida known for its opulence and isolation. The PGA Tour event was played from 1955–1958 at the Mayfair Country Club adjacent to the hotel. The hotel closed in the early 1960s.