Mathiesen is a Danish-Norwegian patronymic surname meaning "son of Mathies" (equivalent of the Biblical Μαθθαιος, cf. English Matthew). Several spelling variants are used, including Matthiesen, Matthiessen, Mathisen, Matthisen. A similar diversity of forms exist for the parallel given name Mathias. There are several people with the surname Mathiesen:
Matthiesen may refer to: