Mariamne II was the third wife of Herod the Great. She was the daughter of Simon Boethus the High Priest. Josephus recounts their wedding thus:
She had one child by Herod, called Herod II or Herod Boethus. Herod II married his niece, Herodias, and by her had a daughter, Salome.
Mariamne II was implicated in the plot of Antipater against her husband (Herod) in 4 BCE. As a result, Herod divorced her and removed her father (Simon Boethus) as high priest. Additionally, her son Herod II was removed from the line of succession in Herod's last will.