Malassezia | |
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Malassezia furfur in skin scale from a patient with tinea versicolor | |
Scientific classification | |
Kingdom: | Fungi |
Division: | Basidiomycota |
Class: | Exobasidiomycetes |
Order: | Malasseziales |
Family: | Malasseziaceae |
Genus: | Malassezia |
Species | |
See text. |
See text.
Malassezia (formerly known as Pityrosporum) is a genus of fungi. Malassezia is naturally found on the skin surfaces of many animals, including humans. In occasional opportunistic infections, some species can cause hypopigmentation or hyperpigmentation on the trunk and other locations in humans. Allergy tests for this fungus are available.
Due to progressive changes in their nomenclature, some confusion exists about the naming and classification of Malassezia yeast species. Work on these yeasts has been complicated because they require specific growth media and grow very slowly in laboratory culture.
Malassezia were originally identified by the French scientist Louis-Charles Malassez in the late 19th century. Raymond Sabouraud identified a dandruff-causing organism in 1904 and called it "Pityrosporum malassez", honoring Malassez, but at the species level as opposed to the genus level. When it was determined that the organisms were the same, the term "Malassezia" was judged to possess priority.
In the mid-20th century, it was reclassified into two species:
In the mid-1990s, scientists at the Pasteur Institute in Paris, France, discovered additional species.
Currently there are at least 14 recognized species:
Thomas Frieden once said his favorite disease was Malassezia furfur because "it's a rash that doesn't cause any harm; it sounds great."
Identification of Malassezia on skin has been aided by the application of molecular or DNA-based techniques. These investigations show that the Malassezia species causing most skin disease in humans, including the most common cause of dandruff and seborrhoeic dermatitis, is M. globosa (though M. restricta is also involved). The skin rash of tinea versicolor (pityriasis versicolor) is also due to infection by this fungus.