lipase A, lysosomal acid, cholesterol esterase (Wolman disease) | |
---|---|
Identifiers | |
Symbol | LIPA |
Entrez | 3988 |
HUGO | 6617 |
OMIM | 278000 |
RefSeq | NM_000235 |
UniProt | P38571 |
Other data | |
EC number | 3.1.1.13 |
Locus | Chr. 10 q23.2-23.3 |
Lysosomal lipase is a form of lipase which functions intracellularly, in the lysosomes.
A deficiency associated with Lysosomal Acid Lipase Deficiency, Wolman disease, and cholesteryl ester storage disease.
Chlorpromazine is an inhibitor of lysosomal lipase.
A genome wide survey suggests that lysosomal lipase A (located at chromosome 10q23.31) is associated with coronary artery disease in humans.