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Lysosomal lipase

lipase A, lysosomal acid, cholesterol esterase (Wolman disease)
Identifiers
Symbol LIPA
Entrez 3988
HUGO 6617
OMIM 278000
RefSeq NM_000235
UniProt P38571
Other data
EC number 3.1.1.13
Locus Chr. 10 q23.2-23.3

Lysosomal lipase is a form of lipase which functions intracellularly, in the lysosomes.

A deficiency associated with Lysosomal Acid Lipase Deficiency, Wolman disease, and cholesteryl ester storage disease.

Chlorpromazine is an inhibitor of lysosomal lipase.

A genome wide survey suggests that lysosomal lipase A (located at chromosome 10q23.31) is associated with coronary artery disease in humans.



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Wikipedia

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