The Lusatian Fault (German: Lausitzer Verwerfung), formerly Lusatian Overthrust (Lausitzer Überschiebung), is the most important geological disturbance zone between the Elbe valley and the Giant Mountains. It is a fault that separates the granite of Lusatia from the Cretaceous sandstones of North Bohemia to the south. It is assumed that there was a fault throw of several hundred metres whereby the northern block was uplifted or upthrust relative to the southern block.
The start of the fault in the west is assessed as being near Oschatz, but it first becomes topographically significant as a steep ledge near Weinböhla. From there it runs eastwards along the northern perimeter of the Dresden Basin and forms the Elbe valley slopes from Radebeul via Dresden to Pirna. From there it continues rather less noticeably along the northern edge of the Elbe Sandstone Mountains via Hohnstein and Hinterhermsdorf. In Hohnstein by the so-called Wartenberg Road (Wartenbergstraße) is the only geological outcrop where the granite of Lusatia lies immediately above the sandstone.
Further east the fault follows the northern boundary of the Lusatian / Zittau Mountains via Jiřetín pod Jedlovou (St. Georgenthal), Waltersdorf and Olbersdorf, where it is most prominent east of the Zittau Mountains.