The Lukuledi is a river in Tanzania, south-eastern Africa. With a total length of 160 km, it rises from the boundary between the Lindi and Mtwara regions.
The Lukuledi runs east-north-eastwards in the region of Lindi, before its mouth in the Indian Ocean near Lindi. It separates the Muera and Makonde plateaus. In the dry season, its discharge reduces substantially, and only the last 40 km of the river's course are never totally dry.
The lower stretch of the Lukuledi forms the boundary between the Northern and Southern Zanzibar-Inhambane coastal forest mosaic ecoregions.
Coordinates: 10°05′S 39°42′E / 10.083°S 39.700°E