Luis Oacpicagigua (O'odham: 'Brain Splicer') or Luis of Sáric (d. 1755) was a Pima Indian (Akimel O'odham) leader in the Spanish province of Sáric, now the far north of the Mexican state of Sonora. Oacpicagigua served as a provincial "Indian governor" and fought for the Spanish government against enemy tribes, but later rebelled against the Spanish in the 1751 Pima Revolt. The revolt failed in 1752, Oacpicagigua and his lieutenant Luis of Pitic were summoned for questioning and subsequently arrested, and Oacpicagigua died in Horcasitas jail in 1755.