Luis Colón de Toledo, 1st Duke of Veragua

Luis Colón de Toledo, 1st Duke of Veragua, 1st Duke of la Vega, 1st Marquis of Jamaica and 3rd Admiral of the Indies (1519/1520/1522 in Santo Domingo – 29 January 1572), was the first son of Diego Colón and María de Toledo y Rojas, and grandson of Christopher Columbus.

After his father's death, a compromise was reached in 1536 in which he was named 3rd Admiral of the Indies and renounced all other rights for a perpetual annuity of 10,000 ducats, the island of Jamaica as a fief, the Dukedom of Veragua estate of 25 square leagues in the Province of Veragua on the Isthmus of Panama, and the titles of 1st Duke of Veragua and 1st Marquess of Jamaica and 1st Duke of La Vega.

He married firstly in 1546 to María de Mosquera y Pasamonte, daughter of Juan de Mosquera and his wife Ofrasina de Pasamonte, and had:

He married secondly in Valladolid, on 19 October 1555, to Ana de Castro Osorio, daughter of Beatriz de Castro Osório, 6th Countess of Lemos and Sárria, and her second husband Alvaro Osorio, without issue.

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