Louis II of Châtillon (d. 26 August 1346, battle of Crécy), son of Guy I, Count of Blois and Margaret of Valois, was count of Blois and lord of Avesnes 1342–1346.
In 1340 in Soissons, he married Jeanne of Avesnes, Countess of Soissons (d. 1350), daughter of John of Avesnes, Lord of Beaumont. They had three children:
Louis was killed at the Battle of Crécy.