"Lose Control (Let Me Down)" is a song performed by American recording artist Keri Hilson featuring Nelly, taken from her second studio album, No Boys Allowed (2010). The song was produced by Norwegian duo StarGate, who wrote the song with Nelly and Ester Dean. "Lose Control" was sent to rhythmic contemporary radio in the United States on May 10, 2011, as the album's fourth single.

"Lose Control" is a song featuring American rapper Nelly, produced by Norwegian duo StarGate. The track opens with a keyboard riff that reverberates. As stated by Nadine Cheung of AOL Music, it features "Hilson's impeccable vocals layered over slinky synths". Karen Tye of Adelaide Now described "Lose Control" as a "B-grade version of Rihanna's "What's My Name?" (2010). Cheung also commented that on the song, Hilson "is instantly attracted to a guy in the club who knows just how to move." During the chorus, Hilson encourages her man to put his hands on her body and lose control. Nelly later delivers his "sexually charged verse" by "confidently telling his lady friend just how he rolls". Robbie Daw of Idolator compared Nelly's line "on the way you shaking your anus", to Kesha's "Cannibal" (2010). After three and a half minutes, "Lose Control" segues into the slow jam "Let Me Down".

Andy Kellman of Allmusic said "Lose Control" was one of the album's direct hits, "despite an anus/famous rhyme from Nelly". Anthony Osei of Complex magazine wrote, "We're a little curious as to why "Lose Control" wasn't her first choice as a single. You really can't go wrong with the production/songwriting combination of StarGate and Ester Dean. Future number-one hit?" Jason Richards of NOW magazine and editors of USA Today, chose "Lose Control" as one of the stand out songs from the album. Aamir Yaqub of SoulCulture.co.uk said the song has a "Rihanna vibe to it probably owed to the production by StarGate". A writer for DesiHits described it as a dance track that was "pure and simple". Andrew Martin of Prefix Mag wrote that "It's unlikely that any new singles off Keri Hilson's No Boys Allowed will have the same chart success as "Pretty Girl Rock". But if any of them can do it, it's 'Lose Control'." Spence D. of IGN Music gave the song a mixed review, stating that it would not fall so flat if the rest of the album had "half the sassy spirit" of "Pretty Girl Rock".

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