The Liverpool Kirkdale by-election, 1910 was a parliamentary by-election held in England on 20 July 1910 for the House of Commons constituency of Liverpool Kirkdale.
The by-election was caused by the death on 3 July 1910 of Charles McArthur, Kirkdale's Conservative Member of Parliament (MP). He had held the seat since a by-election in 1907, having previously been MP for Liverpool Exchange from 1897 to 1906.
The writ for the by-election was moved in the Commons on 12 July by Sir Alexander Acland-Hood, the MP for Wellington.
By 5 July, rumours were circulating in Liverpool that the Conservative candidate would be Alderman Barran, but The Times newspaper reported that these were unfounded. The paper also reported that it was unlikely that a Liberal candidate would be nominated, making the election a two-contest between Labour and the Conservatives, as had been the case in the general elections of 1906 and January 1910. However, the paper noted that Liberal votes would likely be cast almost entirely for the Labour candidate, while Labour were confident that their likely candidate Alexander Gordon Cameron would attract the Protestant votes which were so significant in that area.