The Liverpool Edge Hill by-election of 1979 was a parliamentary by-election held in England on 29 March 1979 to elect a new Member of Parliament (MP) for the House of Commons constituency of Liverpool Edge Hill.
Polling in the by-election took place one day after the government of James Callaghan had lost a vote of no confidence in parliament and slightly over a month before the 1979 general election. The seat had become vacant on the death the previous December of the constituency's Labour Party MP Sir Arthur Irvine, who had held the seat since a by-election in 1947.
The result was a gain for the Liberal Party, represented by David Alton.